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Image and Model Based Analysis of Lung Disease

NCT03764163 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 341

Last updated 2019-01-22

No results posted yet for this study

Summary

The purpose of this research study is to develop CT scanning and image analysis techniques to help define and measure several key properties of the pulmonary system that cannot be obtained by other tests or exams.

Conditions

  • Pulmonary Disease, Chronic Obstructive

Interventions

DIAGNOSTIC_TEST

Pulmonary Function Test

Spirometry, Diffusing Capacity of the Lungs (DLCO), Lung Volumes

DIAGNOSTIC_TEST

CT Scans

volume scans, perfusion scan, ventilation scan

BEHAVIORAL

Questionnaires

Human Subjects Questionnaire, Baseline Dyspnea Index, Chronic Respiratory Questionnaire

DIAGNOSTIC_TEST

MRI

proton scans, hyperpolarized 3-Helium scan

BIOLOGICAL

Xenon gas

ventilation CT scans

Sponsors & Collaborators

  • National Institutes of Health (NIH)

    collaborator NIH

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • Eric A. Hoffman

    lead OTHER

Principal Investigators

  • Eric A Hoffman, PhD · University of Iowa

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
20 Years
Max Age
89 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1997-09-30
Primary Completion
2015-06-05
Completion
2015-06-05
FDA Drug
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03764163 on ClinicalTrials.gov