ADAPT Study: Assessing Diet, Appetite and Physiology Throughout Weight Loss Study)
NCT06174389 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2025-08-29
Summary
Behavioral weight loss programs for obesity can result in weight loss and health benefits. However, behavioral weight loss often stops despite efforts to continue losing weight, this can be called an involuntarily weight loss plateau. This study investigates changes in metabolism and/or the brain that contribute to the occurrence of an involuntary weight loss plateau.
Conditions
Interventions
- BEHAVIORAL
-
Behavioral Weight Loss Program
Behavioral Weight Loss Program is a modified version of the Diabetes Prevention Program.
Sponsors & Collaborators
-
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
collaborator NIH - lead OTHER
Principal Investigators
-
Ellen Schur, MD, MS · University of Washington
-
Marian Neuhouser, PhD, RD · Fred Hutch Cancer Center
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-10-01
- Primary Completion
- 2027-07-31
- Completion
- 2027-07-31
Countries
- United States
Study Locations
More Related Trials
-
Effects of Inhibitory Control Training in Eating Behaviors
NCT03599115 ·Status: COMPLETED ·Phase: NA
-
Food, Activity and Behavior Trial
NCT00640900 ·Status: UNKNOWN ·Phase: NA
-
Remote Delivery of Weight Management for Adults With IDD
NCT03291509 ·Status: COMPLETED ·Phase: NA
-
Behavioral Self-Regulation
NCT00488228 ·Status: COMPLETED ·Phase: NA
-
Is MyPlate Approach to Helping Overweight Patients Lose Weight More Patient-centered?
NCT02514889 ·Status: COMPLETED ·Phase: NA
-
Efficacy of a Web-based Weight Loss Program
NCT01634204 ·Status: UNKNOWN ·Phase: PHASE2
-
Effectiveness Trial of a Dissonance-Based Obesity Prevention Program
NCT01680224 ·Status: COMPLETED ·Phase: NA
-
Nutritional Restriction and Activity Thermogenesis
NCT00065338 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Promote Physical Activity Among Overweight Persons
NCT00313040 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Methods Study to Characterize Early Indicators of Weight Loss in People
NCT00383253 ·Status: COMPLETED ·Phase: NA
-
Effect of Speed of Weight Loss on Compensatory Mechanisms Activated During Weight Reduction
NCT01912742 ·Status: COMPLETED ·Phase: NA
-
Physical Activity in the Treatment of Obesity
NCT00615238 ·Status: COMPLETED ·Phase: NA
-
Computer-Based Weight Maintenance in Primary Care
NCT01946191 ·Status: COMPLETED ·Phase: NA
-
Behavioral Mechanism of Energy Compensation With Exercise
NCT04651218 ·Status: COMPLETED ·Phase: PHASE3
-
Visceral Adiposity, Vagal Tone and Food Preferences: a Pilot Study
NCT06175988 ·Status: RECRUITING
-
Weight Gain Prevention
NCT00606840 ·Status: COMPLETED ·Phase: NA
-
A Pilot Study to Evaluate a Revised Method of Assessing Food in a Commercial Weight Management Program Format
NCT00780468 ·Status: COMPLETED ·Phase: NA
-
Approaches for Improving Long-term Weight Loss
NCT03799289 ·Status: COMPLETED ·Phase: NA
-
Using Technology to Investigate Lapses in a Weight Loss Program Among Individuals With Overweight and Obesity
NCT06023537 ·Status: COMPLETED ·Phase: NA
-
Impact of Self-Monitoring Technology and Interventionist Contact on Weight Loss
NCT01999244 ·Status: COMPLETED ·Phase: NA
-
Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program
NCT04302389 ·Status: COMPLETED ·Phase: NA
-
Control Systems Engineering for Weight Loss Maintenance
NCT06244888 ·Status: RECRUITING ·Phase: PHASE2
-
Comparison of a Technology-based System and an In-person Behavioral Weight Loss Intervention in the Severely Obese
NCT01537796 ·Status: COMPLETED ·Phase: NA
-
Comparison of Two Workplace-Sponsored Obesity Prevention Programs
NCT00481715 ·Status: COMPLETED ·Phase: NA
-
Neurohormonal & Behavioral Correlates of Obesity and Weight Loss
NCT02063451 ·Status: COMPLETED ·Phase: NA