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Effect of Sugar-Free Chewing Gum Containing Tulsi Extract on Salivary Streptococcus Mutans in a Group of Children

NCT06174194 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 33

Last updated 2023-12-18

No results posted yet for this study

Summary

The goal of this clinical trial was to explore how adding Tulsi extract, a natural plant substance, to chewing gum affects the levels of Streptococcus mutans, type of bacteria that cause dental caries, in the saliva of children aged 4 to 11 years. Participants should not use removable prosthetics or orthodontic appliances and had had not used antibiotics in the 2 weeks preceding sample collection.

We want to answer this main question:

Can chewing gum with Tulsi extract significantly reduce the number of Streptococcus mutans bacteria in children's saliva?

Participants tasks:

* Children were asked to chew gum containing Tulsi extract for 5 minutes and then dispose of the gum.
* Two salivary samples were collected from each child: one before gum chewing and another 30 minutes after disposing the gum.

Researchers compared Streptococcus mutans counts in saliva before and after gum chewing to determine if there is a significant reduction in bacterial colonies.

Conditions

  • Dental Caries in Children

Interventions

DIETARY_SUPPLEMENT

Tulsi Gum

The intervention involves participants chewing a specially formulated gum known as "Tulsi Gum" for 5 minutes. Tulsi Gum contains Tulsi extract, a natural substance derived from the Tulsi plant. This extract is recognized for its potential antimicrobial properties. Participants are then required to discard the gum. The study aims to assess the effect of Tulsi Gum on salivary Streptococcus mutans count in children aged 4 to 11 years. This assessment contributes to understanding the potential of Tulsi Gum in preventing dental caries in children.

Sponsors & Collaborators

  • Faculty of Dental Medicine for Girls

    lead OTHER_GOV

Principal Investigators

  • somaya MA Kahwa, Dr · Faculty of Dental Medicine for Girls

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
4 Years
Max Age
11 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-01-01
Primary Completion
2022-08-10
Completion
2022-10-10

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06174194 on ClinicalTrials.gov