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DENTAL GUM TISSUE AGING

NCT06167798 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2023-12-13

No results posted yet for this study

Summary

This is an epidemiological, cross-sectional two-visit study involving 100 Caucasian subjects representing 6 different age groups \[20 to 24 (20s), 30 to 34 (30s), 40 to 44 (40s), 50 to 54 (50s), 60 to 64 (60s), and 70 to 74 (70s)\]. Medically healthy subjects will receive a screening exam to determine their oral status. Subjects without periodontal disease will be enrolled in the study where two 2 mm gingival biopsy will be obtained using punch biopsy from the healthy attached gingiva around upper premolar teeth. Tissues will be processed and analyzed for histological and transcriptomics analyses targeting morphological changes and gene expression in gingival tissues with aging.

Conditions

  • Aging

Interventions

OTHER

biopsy

two 2 mm gingival biopsies were obtained.

Sponsors & Collaborators

  • Procter and Gamble

    collaborator INDUSTRY

  • The Forsyth Institute

    lead OTHER

Eligibility

Min Age
20 Years
Max Age
74 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2013-01-31
Completion
2013-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06167798 on ClinicalTrials.gov