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Psychiatry Research and Motherhood at 6 to 8 (PRAM-P@6to8)

NCT06162689 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 201

Last updated 2025-09-09

No results posted yet for this study

Summary

The goal of this observational study is to examine the relationship between severe perinatal maternal mental illness and stress reactivity and general development of children aged 6 to 8 years. Mothers were previously recruited and assessed during pregnancy and their babies were assessed at 6 days, 8 weeks and 12 months post delivery. This follow-up will assess the occurrence of any psychiatric episodes (e.g., depression, mania, psychosis) in the intervening period. Assessments of the children will include evaluation of their response to a mildly stressful procedure, as well as their physical, cognitive and social-emotional development, and their mental health. Possible factors that may moderate the relationship between the mother's perinatal mental health and the child's stress reactivity and development, including the home environment, adversity, parent-child interaction and maternal and paternal (or co-parent) mental health will also be assessed.

Conditions

  • Perinatal Psychiatry

Sponsors & Collaborators

  • National Institute for Health Research, United Kingdom

    collaborator OTHER_GOV

  • Biomedical Research Centre

    collaborator UNKNOWN

  • King's College London

    lead OTHER

Principal Investigators

  • Paola Dazzan, MD MSc PhD FRCPsych · King's College London

Eligibility

Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-11-15
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06162689 on ClinicalTrials.gov