Interaction Between Genetic Factors and Maternal Stressors During Pregnancy in the Risk of Postpartum Depression
NCT01648816 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3338
Last updated 2023-09-08
Summary
"The prevalence of postpartum depression (PPD) is approximately 13%. PPD is associated with a higher maternal morbidity and mortality, and also with pervasive effects on the emotional, cognitive and behavioral development of the infant.
Stressful life events, socio-demographic and obstetrical risk factors have been associated with the risk of PPD. Genetics risk factors of PPD have also been identified. We are presently studying for the first time how maternal stressors may interact with genetic factors to increase the risk of PPD (Gene x Environment interaction)".
Conditions
Sponsors & Collaborators
-
Assistance Publique - Hôpitaux de Paris
lead OTHER
Principal Investigators
-
Caroline Dubertret, MD, PhD · Assistance Publique - Hôpitaux de Paris
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2011-11-02
- Primary Completion
- 2016-09-04
- Completion
- 2017-07-20
Countries
- France
Study Locations
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