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Cerebral Activation and Apprehension in Patients With Shoulder Instability.

NCT06157788 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 19

Last updated 2023-12-14

No results posted yet for this study

Summary

In a similar study, the investigators demonstrated that shoulder stabilization could allow the brain to partially "recover". Patients with shoulder apprehension underwent clinical and fMRI examination before and one year after shoulder stabilization surgery. Clinical examination showed a significant improvement in postoperative shoulder function compared with preoperative. Coherently, results showed a decreased activation in the left pre-motor cortex postoperatively, demonstrating that stabilization surgery induced improvements both at the physical and at the brain levels, one year postoperatively. Most interestingly, right-frontal pole and right-occipital cortex activity was associated with good outcome in shoulder performance.

Conditions

  • Shoulder Instability

Interventions

DIAGNOSTIC_TEST

functional Magnetic Resonance Imaging and clinical assessment

* fMRI task: In the active condition, video cues were utilized (lasting 10s) depicting everyday activities that trigger shoulder apprehension. Control videos were created to match the previous content, except for the absence of cues inducing shoulder apprehension. Following each video, a visual analog scale appeared for a duration of 2.5s, and participant were asked to rate the level of perceived apprehension, using an MRI-compatible response box. The rating scale consisted of nine steps, ranging from no apprehension to high apprehension. After providing their rating, participants had a rest period during which a fixation cross was displayed visually for 17.5s. Apprehension and control videos were shown in a pseudo-randomized fashion. * General Linear Model Analysis of Task-Related Activation * TICA Analysis of Functional Connectivity * White Matter TBSS of DTI Data * Voxel-based morphometry analysis of T1 images

Sponsors & Collaborators

  • La Tour Hospital

    lead OTHER

Eligibility

Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-04-01
Primary Completion
2023-10-01
Completion
2023-10-01

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06157788 on ClinicalTrials.gov