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Developmental Impacts of Microplastics Exposure in Early Life

NCT06107933 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 40

Last updated 2025-06-10

No results posted yet for this study

Summary

The goal of this observational study is to characterize and evaluate micro- and nano-plastic (MNP) exposures among mothers and infants in mother-infant dyads 1 or 3 months postpartum living in Baltimore, Maryland. The main questions it aims to answer are:

* What MNPs are present in breastmilk and maternal blood samples and in their infants stool sample?
* Are there associations between amount of maternal MNPs in breast milk and mass of MNP particles in infant stool?
* Which environmental and lifestyle factors are most predictive of maternal MNP burden?
* Is infant exposure to MNPs associated with birth weight and postnatal growth trajectories?

Participants will:

* Complete several questionnaires assessing medical histories, lifestyle factors, environmental exposures, eating behaviors, etc.
* Provide biological specimens including: maternal blood, stool, and breastmilk; infant stool
* Clinical visit to have anthropometric measures documented including maternal height and weight, infant weight, length, and skin-fold thickness

Conditions

  • Infant Development
  • Breast Feeding
  • Environmental Exposure

Interventions

OTHER

Observational only

Exposure to micro and nano plastics

Sponsors & Collaborators

  • Emory University

    collaborator OTHER

  • Sonoma Technology, Inc.

    collaborator UNKNOWN

  • Johns Hopkins Bloomberg School of Public Health

    lead OTHER

Principal Investigators

  • Tanya L Alderete, PhD · Johns Hopkins Bloomberg School of Public Health

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2026-06-01
Completion
2027-01-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06107933 on ClinicalTrials.gov