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Looking for a Blood Epigenetic Signature to Predict Female Infertility

NCT06098495 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1456

Last updated 2023-10-24

No results posted yet for this study

Summary

The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality. Specifically, our project aims to build an epigenetic clock for MGCs by using outcomes that are certainly related to female fertility. The validation of such findings will be carried out on peripheral blood in order to guarantee its non-invasiveness and allow for any clinical transferability. In order to identify a blood epigenetic signature able to predict female infertility, we planned to explore the problem from different points of view by conducting several studies in different settings.

Conditions

  • Female Infertility

Interventions

GENETIC

search for epigenetic profile of infertility

examine the epigenetic profile of DNA extracted from MGCs and blood sample

Sponsors & Collaborators

  • Università Vita-Salute San Raffaele

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
43 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-10-16
Primary Completion
2026-10-16
Completion
2026-10-16

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06098495 on ClinicalTrials.gov