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Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn

NCT06090617 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 35

Last updated 2024-03-19

No results posted yet for this study

Summary

WHYSKI is a prospective within-patient observational clinical study designed to test the hypothesis that alterations of Na+, K+, water, and the lympho-angiogenetic transcription factor Tonicity Enhancing Binding Protein (TonEBP) mRNA take place in the interstitium of the skin compartment of patients with arterial hypertension due to primary aldosteronism in whom hypertension can be surgically cured.

Conditions

  • Hyperaldosteronism
  • Hypertension
  • Aldosterone-producing Adenoma
  • Aldosteronism
  • Aldosterone Disorder
  • Essential Hypertension
  • Bilateral Adrenal Hyperplasia
  • Conn Adenoma

Interventions

PROCEDURE

Skin Biopsy

Skin biopsies were obtained in all recruited patients.

PROCEDURE

Video-laparoscopic adrenalectomy

Video-laparoscopic adrenalectomy in those with unilateral PA. (PA group 1)

Sponsors & Collaborators

  • University Hospital Padova

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-01-01
Primary Completion
2024-04-01
Completion
2025-01-01

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06090617 on ClinicalTrials.gov