Implant Placement With Corticocancellous Bone Block vs Mineralized Plasmatic Matrix in Maxillary Sinus Lifting

Summary

Maxillary sinus floor elevation is a predictable and effective procedure for increasing the height of the residual bone in the posterior maxilla. The sinus lift procedure is basically performed using Conventional lateral sinus floor elevation (CLSFE) when RBH \< 5 mm.

The use of autogenous corticocancellous bone block allows the simultaneous placement of an implant in the severely atrophic maxilla. Autogenous corticocancellous block will be applied in these patients to decrease the number of surgical interventions and the complications related to the surgery, without any additional risk, as well as to provide graft stabilization with the implant itself, using a mechanism similar to that of a screw and nut. Although the traditional application of sticky bone inside the sinus gives the benefit of moldable shaping and accurate fit into the recipient bony cavity which hardens and allows for implant osteotomy and installation with adequate implant stability. Limited comparative studies of both techniques had been introduced to the literature. This study is aimed to compare the quantity of bone gain after open sinus lift and augmentation using autogenous corticocancellous bone blocks from the chin area versus autogenous particulate mineralized plasmatic matrix (sticky bone) graft used as control group.

The primary outcome which is amount of bone gain will be measured and secondary stability of the implant.

Conditions

• Maxillary Sinus Floor Elevation

Interventions

PROCEDURE

Open sinus lifting

Sinus lateral window to graft the floor of the sinus using sinus red diamond stone

PROCEDURE

Collecting blood sample

Blood sample is collected to harvest PRP and PRF

PROCEDURE

Bone graft harvesting

Bone graft harvesting from the chin area

PROCEDURE

Autogenous corticocancellous block graft

Simultaneous implant placement with sinus lifting and grafting using autogenous corticocancellous block, stabilized inside the sinus using clamp or screws that will be removed before closure

PROCEDURE

Mineralized plasmatic matrix graft

Simultaneous implant placement with sinus lifting and grafting using mineralized plasmatic matrix that is formed using PRP of the patient mixed with particulate autogenous graft from the chin area

DEVICE

Centrifuge

Centrifuge will be needed to get the PRP in the Comparator group and PRP in both groups

DEVICE

ACM bur

Auto Chip Maker will be used to collect the autogenous particulate bone graft for the sticky bone graft

Sponsors & Collaborators

• Cairo University

  lead OTHER

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

70 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2023-12-01

Primary Completion

2024-04-01

Completion

2024-06-01