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Premorbid Personality Profile of Patients With Cognitive and Behavioral Disorders

NCT06059313 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2023-10-03

No results posted yet for this study

Summary

Damages in frontal area present in neurodegenerative disease (frontotemporal degeneration, frontal variant of Alzheimer disease) and in psychiatric disease (bipolar disorder) can affect behavior and cognition including social cognition. Symptoms vary both quantitatively and qualitatively from disease to another and from person to person. It cannot be completely excluded that in some cases, factors of susceptibility such as premorbid personality traits lead to frontal fragility.

The study will assess the relationship between premorbid profile using NEO-PI 3 inventory and cognitive and behavioral/psychobehavioral manifestations in patients with behavioral variant of frontotemporal disorder (bvFTD), phenocopy frontotemporal dementia (phFTD), frontal variant of Alzheimer disease, bipolar disorder characterized with frontal damages.

Conditions

  • Behavioral Variant of Frontotemporal Disorder (bvFTD)
  • Phenocopy Frontotemporal Dementia (phFTD)
  • Frontal Variant of Alzheimer Disease
  • Bipolar Disorder

Interventions

OTHER

Submission of the NEO-PI-3 questionnaire

The questionnaire contains 240 statements. For each statement, the patient chooses the answer that best corresponds to their choice (FD: strongly disagree - D: disagree - N: neutral - A: agree - FA: strongly agree).

OTHER

Submission of the Interpersonal Reactivity Index questionnaire (IRI)

The test assesses two cognitive and two affective components of empathy that influence each other and affect attitudes and behaviors toward others.

Sponsors & Collaborators

  • Nantes University Hospital

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-10-01
Primary Completion
2026-10-01
Completion
2027-02-01

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06059313 on ClinicalTrials.gov