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FCV vs PCV in Moderate to Severe ARDS

NCT06051188 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2023-12-01

No results posted yet for this study

Summary

The goal of this clinical trial is to compare flow-controlled ventilation (FCV) and pressure-controlled ventilation (PCV) in patients with moderate to severe acute respiratory distress syndrome on the intensive care unit.

The main questions it aims to answer are:

* Is the mechanical power during flow-controlled ventilation lower than during pressure-controlled ventilation
* To gain more understanding about other physiological effects and potential benefits of flow-controlled ventilation in comparison to pressure-controlled ventilation (o.a. the end-expiratory lung volume and homogeneity of ventilation).

Participants will be randomized between two ventilation mode sequences, being 90 minutes of FCV followed by 90 minutes of PCV or vice versa.

Conditions

  • Acute Respiratory Distress Syndrome
  • Ventilator Lung

Interventions

DEVICE

Flow-controlled ventilation

Flow-controlled ventilation (FCV)

Sponsors & Collaborators

Principal Investigators

  • Rik Endeman, Dr · Erasmus Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-12
Primary Completion
2025-05-31
Completion
2026-05-31

Countries

  • Netherlands

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06051188 on ClinicalTrials.gov