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Characterization of Bovine Adrenal Medulla as a Model of Non-histaminergic Itch

NCT06036589 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2023-09-14

No results posted yet for this study

Summary

With this experiment, the experimenter wish evaluate the role of TRPA1 on non-histaminergic itch induced by BAM8-22

Conditions

  • Itch

Interventions

DRUG

CA and BAM8-22

CA (tran-cinnamaldheyde) solution (in ethanol 5%) application and BAM8-22 with inactivate cowhage spicules 20 µl of BAM8-22 will be applied to a previously determined area on the volar forearm using inactivate cowhage spicules

DRUG

Vehicle and BAM8-22 application

Vehicle (ethanol) application and BAM8-22 with inactivate cowhage spicules 20 µl of BAM8-22 will be applied to a previously determined area on the volar forearm using inactivate cowhage spicules

DRUG

CA

CA (tran-cinnamaldheyde) solution (in ethanol 5%) application to a previously determined area on the volar forearm

DRUG

vehicle

Vehicle (ethanol) application and inactivate cowhage spicules will be applied to a previously determined area on the volar forearm

Sponsors & Collaborators

  • Aalborg University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-03-10
Primary Completion
2022-05-30
Completion
2022-10-30

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06036589 on ClinicalTrials.gov