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Characterization of BAM8-22 as a New Surrogate Model of Non-histaminergic Itch

NCT04588532 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2021-07-21

No results posted yet for this study

Summary

With this experiment, the experimenter wish to asses if substance BAM8-22 (Bovine Adrenal Medulla) induce non-histaminergic itch.

Conditions

  • Itch

Interventions

DRUG

BAM8-22

Bovine Adrenal Medulla will be applied to 2 previously determined area on the volar forearm (one alone and one in combination with doxepin)

DRUG

Histamine

histamine will be applied to 2 previously determined area on the volar forearm (one alone and one in combination with doxepin)

DRUG

Cowhage (Mucuna Pruriens)

cowhage spicules will be applied to 2 previously determined area on the volar forearm (one alone and one in combination with doxepin)

DRUG

Doxepin

Doxepin cream (antihistamine) will be applied in 4 areas on the volar forearm

Sponsors & Collaborators

  • Aalborg University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-10-01
Primary Completion
2021-05-01
Completion
2021-06-01

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04588532 on ClinicalTrials.gov