The Novel 18F-labeled MAO-B PET Tracer Study in Parkinsonism Patients
NCT06010290 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 80
Last updated 2023-08-24
Summary
This study mainly aims to prospectively evaluate the changes of reactive astrogliosis in Parkinsonism patients of Chinese population by the novel 18F-labeled MAO-B PET tracer.
Conditions
- Parkinson Disease
Interventions
- DRUG
-
18F-SMBT-1
Each participant receives intravenous injection of 18F-SMBT-1, and undergo PET/CT imaging within the special time. 18F-FP-CIT and 18F-FDG PET/CT are used to assess the change of cerebral dopamine transporters and glucose metabolism for auxiliary diagnosis.
Sponsors & Collaborators
-
Anhui Provincial Hospital
lead OTHER_GOV
Principal Investigators
-
Qiang Xie, MD · The First Affiliated Hospital of China University of Science and Technology
Eligibility
- Min Age
- 40 Years
- Max Age
- 90 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-11-30
- Primary Completion
- 2023-12-31
- Completion
- 2023-12-31
Countries
- China
Study Locations
More Related Trials
-
MRgFUS Pallidothalamic Tractotomy for Therapy-Resistant Parkinson's Disease
NCT04996992 ·Status: NOT_YET_RECRUITING
-
Application of 18F-CP6A PET Imaging in Synucleinopathies
NCT06827821 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Assessing Cholinergic Innervation in Parkinson's Disease Using the PET Imaging Marker [18F]Fluoroethoxybenzovesamicol
NCT02952391 ·Status: UNKNOWN
-
NMR Based Metabolomic Study of Serum Biomarkers in Patients With Parkinson's Disease and Atypical Parkinsonian Syndrome
NCT06490926 ·Status: RECRUITING
-
The Effect of Dual-site Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
NCT05925296 ·Status: UNKNOWN ·Phase: NA
-
Targeting Monoaminergic Neuronal Networks in the Parkinsonian Patients After Carbon Monoxide Intoxication
NCT02138864 ·Status: UNKNOWN ·Phase: PHASE3
-
PET/MR Imaging in Patients With Short and Long Standing Parkinson's Disease
NCT02801110 ·Status: UNKNOWN
-
The Differential Diagnosis of Parkinson's Disease and Parkinsonism by Positron-emission Tomography
NCT01824056 ·Status: COMPLETED ·Phase: PHASE2
-
Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR
NCT05205291 ·Status: RECRUITING
-
7.0T Magnetic Resonance Imaging Study of Parkinson's Disease
NCT06449404 ·Status: RECRUITING
-
Evaluation of Neuroinflammation in Parkinson's Disease Using 18F-NOS PET/CT
NCT04062526 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
[18F] - FD17 PET Imaging of α-synuclein: A Clinical Study in α-synucleinopathy Patients
NCT06738862 ·Status: COMPLETED
-
Serotonin Release in Premotor and Motor PD
NCT05516732 ·Status: RECRUITING
-
PET Imaging in Parkinson Disease Dementia
NCT01052350 ·Status: ACTIVE_NOT_RECRUITING
-
Study on Serum Cystatin C and PET-DAT in Patients With Parkinson's Disease
NCT04926909 ·Status: UNKNOWN
-
PET Study of Non-Motor Symptoms of Parkinson Disease
NCT01565473 ·Status: COMPLETED
-
Measure of Microglial Activation in the Brain of Parkinson Disease Patients With PET
NCT02319382 ·Status: UNKNOWN ·Phase: NA
-
Biomarkers in Parkinsonian Syndromes
NCT06501469 ·Status: RECRUITING
-
The Profile of the Depression and it's Intervention Strategy in Patients With Parkinson's Disease in China
NCT03026595 ·Status: UNKNOWN
-
Efficacy and Safety of F-18 FPCIT PET in Parkinson's Disease and Essential Tremor Patients
NCT00468078 ·Status: COMPLETED ·Phase: PHASE3
-
Neuroimaging Studies of Depression in Parkinson's Disease
NCT00518258 ·Status: COMPLETED
-
Predictive and Diagnostic Value of Tau and Beta-amyloid Markers in the Dementia of Parkinson's Disease
NCT02243982 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
The Efficacy and Mechanism of SMA+M1 Repetitive Transcranial Magnetic Stimulation on Freezing of Gait in PD
NCT06415682 ·Status: COMPLETED ·Phase: NA
-
The Effect of Multi-target Magnetic Stimulation on Freezing Gait in PD
NCT05174299 ·Status: UNKNOWN ·Phase: NA
-
Imaging Studies of Cognitive Impairment in Parkinson s Disease
NCT01862744 ·Status: COMPLETED