Parathyroid Tumor Clonal Status
NCT05997810 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 839
Last updated 2026-05-12
Summary
To define the frequency of monoclonal-X and polyclonal-X tumors in hyperparathyroid disorders patients having PTX and to define the relationship between parathyroid tumor clonal status and multiple gland neoplasia (MGN), we will compare surgical and pathologic outcomes to tumor clonal status in a multicenter cohort of patients having bilateral neck exploration (BNE) and PTX (primary objectives).
Conditions
- Parathyroid Tumor
- Primary Hyperparathyroidism
- Secondary Hyperparathyroidism (SHPT)
- Tertiary Hyperparathyroidism
Sponsors & Collaborators
-
Washington University School of Medicine
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-07-28
- Primary Completion
- 2031-01-31
- Completion
- 2032-01-31
Countries
- United States
Study Locations
More Related Trials
-
A Real-world Study of the Efficacy and Safety of PD-1 Inhibitors Combined With Chemoradiotherapy in Lung Metastatic Nasopharyngeal Carcinoma
NCT07062484 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Phase II Clinical Study to Evaluate the Safety, Pharmacokinetic Profile, and Preliminary Efficacy of IMM2510 in Combination with Chemotherapy As First-line Treatment in Subjects with Non-small Cell Lung Cancer or Triple-negative Breast Cancer
NCT06746870 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Radiotherapy Combined With PD-1 Monoclonal Antibody and Capecitabine in the Treatment of Nasopharyngeal Carcinoma
NCT05290194 ·Status: RECRUITING ·Phase: PHASE2
-
A Prospective, Single-arm Clinical Study of Pabrolizumab in Combination With Cisplatin + 5-FU for the Neoadjuvant Treatment of Unresectable, Advanced Squamous Carcinoma of the Temporal Bone Single-arm Clinical Study
NCT05444673 ·Status: UNKNOWN ·Phase: PHASE4
-
Neoadjuvant Toripalimab or Toripalimab in Combination With Carboplatin and Nab-paclitaxel in Untreated HNSCC (HNSCC-002)
NCT04807140 ·Status: RECRUITING ·Phase: PHASE2
-
Clinical Study of Neoadjuvant PD-1 Antibody (Toripalimab) Plus Chemotherapy for Locally Advanced Thymic Epithelial Tumor
NCT04667793 ·Status: UNKNOWN ·Phase: PHASE2
-
An Observational Clinical Study of Stereotactic Radiotherapy for Advanced Non-Small Cell Lung Cancer With Stable Disease After PD-1 Inhibitor Treatment
NCT05486650 ·Status: RECRUITING
-
Targeted or Chemotherapy Combined With Immunotherapy Versus Chemotherapy for PD-1 Inhibitor Refractory R/M NPC
NCT05549466 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant PD-1 Inhibitor Combined With Cetuximab and Platinum in Resectable Locally Advanced Hypopharyngeal Carcinoma
NCT06151743 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Anlotinib in Patients With Radioiodine Refractory Differentiated Thyroid Cancer
NCT06062563 ·Status: UNKNOWN ·Phase: NA
-
ImmunoPET Targeting Trophoblast Cell-Surface Antigen 2 (Trop-2) in Thyroid Cancer
NCT06465017 ·Status: TERMINATED ·Phase: NA
-
Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid Tumors
NCT05145907 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Anti-PD1 Monoclonal Antibody Combined With Nimotuzumab and Capecitabine in Patients With First-line Platinum-resistant Recurrent/Metastatic Nasopharyngeal Carcinoma
NCT06259721 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy Study of Neoadjuvant Chemotherapy With Chemoradiation Therapy for Nasopharyngeal Carcinoma
NCT01536223 ·Status: UNKNOWN ·Phase: PHASE3
-
Clinical Study of Combined Radical Operation With Postoperative Adjuvant Chemotherapy and Prophylactic Cranial Irradiation in pT1-2N0M0 Stage of Small Cell Lung Cancer
NCT03514849 ·Status: RECRUITING ·Phase: NA
-
PD-1 Inhibitors Plus Chemoradiotherapy for Metastatic Nasopharyngeal Carcinoma: an Open-label Single-arm, Phase II Trial
NCT05520814 ·Status: UNKNOWN ·Phase: PHASE2
-
Neoadjuvant Chemotherapy Plus Toripalimab in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
NCT05813626 ·Status: RECRUITING ·Phase: PHASE2
-
Neoadjuvant Chemotherapy Combined With Finotonlimab in the Treatment of Locally Advanced Hypopharyngeal Carcinoma
NCT07248956 ·Status: RECRUITING ·Phase: PHASE2
-
Radiotherapy Combined With Thymosin for Metastatic NSCLC Patients Who Showed Stable Disease After First Line TKI Therapy
NCT02787447 ·Status: UNKNOWN ·Phase: PHASE2
-
The Efficacy and Safety of Neoadjuvant Low-dose Radiotherapy Combined With Chemoimmunotherapy in Locally Advanced HNSCC
NCT05343325 ·Status: RECRUITING ·Phase: PHASE2
-
A Multicenter, Prospective, Phase III Randomized Controlled Clinical Study for the Treatment of N2-3 Nasopharyngeal Carcinoma Patients
NCT04061278 ·Status: UNKNOWN ·Phase: PHASE3
-
SBRT Followed by Chemoimmunotherapy of Toripalimab Plus Docetaxel and Cisplatin for Larynx Preservation in Patients with Locally Regionally Advanced Squamous Cell Carcinoma of the Larynx and Hypopharynx
NCT06611137 ·Status: RECRUITING ·Phase: PHASE2
-
GP-induced Chemotherapy Combined With IMRT and TPF-induced Chemotherapy Combined With IMRT in the Treatment of Distant Metastatic Nasopharyngeal Carcinoma
NCT03723343 ·Status: UNKNOWN
-
TPC Combined With Cadonilimab VS. TPC Alone in Anti-PD-1 Resistant Recurrent or Metastatic Nasopharyngeal Carcinoma
NCT06664983 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Neoadjuvant Immune Checkpoint Inhibitor Combined With Chemotherapy in Non-small Cell Lung Cancer
NCT04945200 ·Status: UNKNOWN