GP-induced Chemotherapy Combined With IMRT and TPF-induced Chemotherapy Combined With IMRT in the Treatment of Distant Metastatic Nasopharyngeal Carcinoma
NCT03723343 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 146
Last updated 2018-10-29
Summary
Mainly compared with GP induction chemotherapy combined with IMRT and TPF induction chemotherapy combined with IMRT in the treatment of nasopharyngeal carcinoma, the cure rate, remission rate, treatment of distant metastases and lymph node metastasis, quality of life improvement rate, etc.
Conditions
- Advanced Nasopharyngeal Carcinoma
Interventions
- DRUG
-
GP+IMRT
Gemcitabine 1000 mg/m2 intravenously, d1\&d8 +Cisplatin 80 mg/m2 intravenously, d1 21\~28 days/cycle, 4 patients with oligometastasis, 6 cycles with multiple metastases
- DRUG
-
TPF+IMRT
Docetaxel: 75mg/m2 intravenous drip, d1+Cisplatin75mg/m2 intravenous drip, d1\~d5+5-fluorouracil 750mg/m2/d intravenous drip, d1\~d521\~28 days/cycle, patients with oligometastasis take 4 cycles, moreTransfer patients for 6 cycles
Sponsors & Collaborators
-
Guiyang Medical University
lead OTHER
Principal Investigators
-
Jinhua Long, Master · Guizhou Provincial Cancer Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2018-10-18
- Primary Completion
- 2021-06-30
- Completion
- 2021-06-30
Countries
- China
Study Locations
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