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Immuno-virological Evaluation of Persons Living With HIV (PLWH)

NCT05973825 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2024-07-15

No results posted yet for this study

Summary

This is a dual arm (arm 1 and arm 2) multi-centric non-randomized (prospective) study.

Two new multicentric cohorts will be set up in 4 Belgian HIV reference centers (UZ Gent, UZ Brussel, University Hospital Liege and St. Pierre Hospital Brussels): cohort 1 will comprise PLWH in whom ART was initiated during acute HIV infection minimum 3 years ago but no more than 10 years ago (short-term ART cohort); cohort 2 will comprise PLWH on ART since \>20 years (long-term ART cohort). Participants will be included based on suppressed viremia and uninterrupted ART since initiation. Participants will undergo one blood sampling and one leukapheresis. In and exclusion criteria are described below.

Conditions

Interventions

PROCEDURE

Leucapheresis

leucapheresis is a procedure in which a large amount of blood cells are obtained by an apheresis procedure

Sponsors & Collaborators

  • Vrije Universiteit Brussel

    collaborator OTHER

  • Centre Hospitalier Universitaire Saint Pierre

    collaborator OTHER

  • Centre Hospitalier Universitaire de Liege

    collaborator OTHER

  • Universitair Ziekenhuis Brussel

    collaborator OTHER

  • Université Libre de Bruxelles

    collaborator OTHER

  • KU Leuven

    collaborator OTHER

  • University Hospital, Ghent

    lead OTHER

Principal Investigators

  • Linos vandekerckhove · UZ Gent

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-09-01
Primary Completion
2027-07-12
Completion
2029-07-12

Countries

  • Belgium

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05973825 on ClinicalTrials.gov