Duration of Dual Antiretroviral Therapy in Virologically Suppressed People Living With HIV and Factors Associated With Switching to Tritherapy : a Real-life Cohort
NCT06107140 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 580
Last updated 2023-11-01
Summary
HIV infection requires lifelong continuous antiretroviral (ARV) treatment. The efficacy of current ARV treatments makes it possible to propose strategies for reducing the cumulative exposure to ARVs, side effects and costs. And so improve the quality of life of people living with HIV (PLHIV). However, in the real world, less regular adherence to treatment, more heavily pre-treated patients and resistance to treatment make these dual therapies prescribed beyond the strict framework of clinical trials. This can lead to undesirable side effects. From the perspective of personalized medicine, it seems to be important to determine which patients are receiving dual ARV therapy, and which patients remain on it for a long time. Identifying prognostic factors would enable us to adapt therapeutic management.
Conditions
- HIV Infections
Interventions
- OTHER
-
dual therapy
The evaluation will focus on the retention of patients living with hiv on dual antiretroviral therapy.
Sponsors & Collaborators
-
Tourcoing Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2011-01-01
- Primary Completion
- 2023-05-01
- Completion
- 2023-05-01
Countries
- France
Study Locations
More Related Trials
-
Second-line Therapy Antiretroviral in Patients Who Failed Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) - Based Regimens
NCT00627055 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Inflammatory Markers and Incidence of Comorbidities in Patients on Antiretroviral Therapy With Second-generation Anti-integrase Drugs on Triple Versus Dual Therapy
NCT05699785 ·Status: RECRUITING ·Phase: NA
-
Study to Evaluate Switching From Regimens Consisting of a Ritonavir-boosted Protease Inhibitor (PI) and Two Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to a Fixed-dose Tablet Containing Emtricitabine/Rilpivirine/Tenofovir DF
NCT01252940 ·Status: COMPLETED ·Phase: PHASE3
-
Strategic Timing of Antiretroviral Treatment
NCT00867048 ·Status: COMPLETED ·Phase: PHASE4
-
Early and Intermittent Antiretroviral Therapy in Naive HIV Infected Adults
NCT00820118 ·Status: COMPLETED ·Phase: PHASE2
-
A Trial With TMC278-TIDP6-C222 for Continued TMC278 Access in Patients Infected With Human Immunodeficiency Virus-1
NCT01266902 ·Status: COMPLETED ·Phase: PHASE3
-
Nevirapine vs Ritonavir-boosted Lopinavir in ART Naive HIV-infected Adults in a Resource Limited Setting
NCT01772940 ·Status: COMPLETED ·Phase: PHASE4
-
Dolutegravir-based Dual Therapies in HIV-infected Patients With Virological Suppression
NCT02491242 ·Status: COMPLETED
-
Determining the Effects of Observed and Self-Administered Drug Regimens in HIV Infected Adults
NCT00608569 ·Status: COMPLETED ·Phase: NA
-
Intermittent Therapy in HIV-1 Infected Patients With Successful Viral Suppression Under Highly Active Antiretroviral Therapy (HAART)
NCT00122551 ·Status: TERMINATED ·Phase: PHASE3
-
DORAvirine Versus DOlutegravir Based Antiretroviral Regimens in Treatment-naïve People Living With HIV-1 Infection
NCT06203132 ·Status: RECRUITING ·Phase: PHASE3
-
Study to Evaluate Switching From a Regimen Consisting of the Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate Single-Tablet Regimen (STR) to the Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate STR
NCT01286740 ·Status: COMPLETED ·Phase: PHASE2
-
Immediate Versus Deferred Antiretroviral Therapy in HIV-infected Patients Presenting With Acute AIDS-defining Events
NCT01417949 ·Status: COMPLETED ·Phase: PHASE4
-
Intermittent Versus Continuous Medication in the Treatment of HIV
NCT00001967 ·Status: COMPLETED ·Phase: PHASE4
-
Switch Study to Evaluate F/TAF in HIV-1 Positive Participants Who Are Virologically Suppressed on Regimens Containing FTC/TDF
NCT02121795 ·Status: COMPLETED ·Phase: PHASE3
-
ART First-line Treatment Durability in Russia
NCT04253119 ·Status: COMPLETED
-
D/C/F/TAF Versus COBI-boosted DRV Plus FTC/TDF in HIV-1 Infected, Antiretroviral Treatment Naive Adults
NCT01565850 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate Switching From a Regimen of Two Nucleos(t)Ide Reverse Transcriptase Inhibitors (NRTI) Plus a Third Agent to a Fixed Dose Combination (FDC) of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF), in Virologically-Suppressed, HIV-1 Infected African American Participants
NCT03631732 ·Status: COMPLETED ·Phase: PHASE3
-
Dynamics of Drug Resistance-associated Mutations in HIV-1 DNA Reverse Transcriptase Clearance During Effective Antiretroviral Therapy
NCT04448158 ·Status: COMPLETED
-
Adherence-Suppression-Resistance Relationships for Atripla Compared to Historical Antiretroviral Regimens
NCT01006005 ·Status: COMPLETED
-
Evaluation of the Efficacy and Safety Between Two Antiretroviral Regimens, in HIV-1-infected Treatment-naïve Subjects With Low CD4 Counts
NCT01928407 ·Status: COMPLETED ·Phase: PHASE4
-
Efficacy and Tolerability of an Antiretroviral Bi-Therapy in HIV Infected Patients With Multidrug Resistance
NCT00120783 ·Status: TERMINATED ·Phase: PHASE2
-
Administration of High Doses of Antiretroviral Drugs to Eliminate the Latent HIV-1 Reservoir
NCT06640192 ·Status: RECRUITING ·Phase: PHASE2
-
Immediate Initiation of Antiretroviral Therapy During "Hyperacute" HIV Infection
NCT02656511 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
REal-Life Cohort With DOlutegravir + LAmivudina
NCT04638686 ·Status: COMPLETED