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Early Treatments for Preventing Occlusal Caries Lesions

NCT05969756 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 132

Last updated 2026-05-14

No results posted yet for this study

Summary

Sealants effectively arrest non-cavitated caries lesions on the fully erupted occlusal surface of permanent teeth. However, the clinical effectiveness of sealants is uncertain in preventing occlusal caries lesions in partially erupted permanent molars. This study aims to evaluate the progression of caries, the degree of retention, survival rate, and quality of the remnant after applying conventional total-etch resinous sealant and self-etch sealant in erupting molars.

Conditions

  • Caries; Initial
  • Occlusal Caries
  • Caries,Dental

Interventions

DRUG

Fluoride varnish

Thirty-eight permanent molars will receive 5% sodium fluoride varnish application every three months

DRUG

Conventional etch and rinse sealant

Thirty-eight permanent molars will receive conventional etch and rinse sealant

DRUG

Self-etch sealant

Thirty-eight permanent molars will receive self-etch sealant

Sponsors & Collaborators

  • Hue University of Medicine and Pharmacy

    lead OTHER

Principal Investigators

  • Van Nhat Thang Le, DDS, PhD · Hue University of Medicine and Pharmacy

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
5 Years
Max Age
14 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-07-31
Primary Completion
2024-10-10
Completion
2024-10-15

Countries

  • Vietnam

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05969756 on ClinicalTrials.gov