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Effectiveness of Different Remineralizing Strategies on the Management of Early Carious Lesions in Primary Teeth

NCT06566833 · Status: COMPLETED · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2025-01-29

No results posted yet for this study

Summary

the primary aim of the study is remineralization of early carious lesions in primary teeth using different remineralizing agents of different remineralizing strategies when applied in an intensive mode. The secondary aim of the study is to compare their antibacterial effect against streptococcus mutans and their effect on reducing the size of the lesions.

Conditions

  • White Spot Lesion

Interventions

DRUG

self assmbling peptide p11-4 combined with 0.05% fluoride

biomimetic remineralizing agent

DRUG

Casein phosphopeptide amorphous calcium phosphate

remineralizing agents that acts as a fluoride booster

DRUG

5% sodium fluoride varnish

remineralizing agent that is used as a gold standard for remineralization

Sponsors & Collaborators

  • Alexandria University

    lead OTHER

Principal Investigators

  • karin dowidar, professor · faculty of Dentistry, Alexandria university, Egypt

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
3 Years
Max Age
6 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-08-15
Primary Completion
2024-10-15
Completion
2024-10-15
FDA Drug
Yes

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06566833 on ClinicalTrials.gov