Maternal Endocrine System and Metabolic Diseases and Offspring Health: Prediction Within a Birth Cohort
NCT05952739 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 300
Last updated 2023-11-24
Summary
The incidence of metabolic diseases in pregnant women is increasing rapidly, and the risk of metabolic diseases in children is also increasing. However, there is a lack of early predictive indicators for metabolic diseases in children, which cannot effectively prevent and treat metabolic diseases in children. This project will establish a clinical database and a long-term follow-up biological bio-bank through the follow-up of metabolic indicators before and during pregnancy, and form an early warning system for the effects of maternal endocrine and metabolic diseases on the metabolism of offspring. It will not only help to warn the impact of maternal endocrine system and metabolic diseases on the metabolism of offspring, but also build a transformation platform for the study of maternal endocrine and metabolic diseases and metabolic health of offspring, which has important clinical value for curbing the rapid growth of metabolic diseases such as diabetes and obesity in China. It is expected to provide an important theoretical basis for the window period of prevention and treatment of endocrine and metabolic diseases in China.
Conditions
- Thyroid Dysfunction
- Diabetes Mellitus
Sponsors & Collaborators
-
Peking Union Medical College Hospital
lead OTHER
Principal Investigators
-
Xinhua Xiao · Key Laboratory of Endocrinology, Ministry of Health, Department of Endocrinology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-08-01
- Primary Completion
- 2025-09-30
- Completion
- 2025-09-30
Countries
- China
Study Locations
More Related Trials
-
Maternal Hypertriglyceridaemia Study
NCT02479113 ·Status: UNKNOWN
-
Iodine Nutrition During Pregnancy and Related Neonatal Physical Development
NCT02586220 ·Status: COMPLETED
-
Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol
NCT02322177 ·Status: COMPLETED
-
Metabolic and Endocrine Status in Women With Prior Preterm Birth
NCT01355536 ·Status: COMPLETED
-
Prediction of Preeclampsia by Comprehensive Markers.
NCT03665623 ·Status: COMPLETED
-
Evolution of Maternal Weight During Pregnancy and Influence on the Endothelial Function in Her Offspring
NCT02992106 ·Status: COMPLETED ·Phase: NA
-
Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus
NCT03570632 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Chinese Pregnant Woman Cohort Study (Offspring Follow-up)
NCT04444791 ·Status: UNKNOWN
-
Gestational Diabetes Mellitus and Implications for Cardiovascular Disease Risk
NCT00550979 ·Status: UNKNOWN
-
Biomarkers for Inborn Errors of Metabolism
NCT04098198 ·Status: COMPLETED
-
Study on Early Genetic Screening and Precise Strategy of Neonatal Critical Illness
NCT04905537 ·Status: RECRUITING
-
Mother Infant Nutrition Study
NCT04132310 ·Status: ENROLLING_BY_INVITATION
-
No-worry Baby Project
NCT03922087 ·Status: COMPLETED
-
Healthy Start: Exploring the Fuel-mediated Programming of Neonatal Growth
NCT02273297 ·Status: RECRUITING
-
Improving Women's and Children's Health Via Biobanking and Electronic Registry
NCT03938129 ·Status: COMPLETED
-
Environmental Factors and Embryonic Development Project
NCT04182503 ·Status: UNKNOWN
-
Regulation Of Maternal Fuel Supply And Neonatal Adiposity
NCT00826904 ·Status: COMPLETED
-
Association of Gestational Cardiovascular Health With Pregnancy Outcomes
NCT05776082 ·Status: RECRUITING
-
The Important Project of Obese Pregnant Women
NCT05160662 ·Status: UNKNOWN ·Phase: NA
-
Monitoring and Outcome Measures in Asthmatics and Smokers During Pregnancy
NCT00425880 ·Status: WITHDRAWN
-
Evaluation and Validation of New Biomarkers by Mass Spectrometry
NCT01025973 ·Status: COMPLETED
-
Measuring Outcomes of Maternal COVID-19-related Prenatal Exposure
NCT04540029 ·Status: COMPLETED
-
Assessment of Oxidative Stress Contents in Jordanian Pregnant Women With Preeclampsia
NCT07119034 ·Status: COMPLETED
-
The Pilot Study of High-throughput Sequencing in Neonatal Birth Defects
NCT03984266 ·Status: COMPLETED
-
A Multicenter Cohort Study on Maternal and Infant Microecology and New Targets for Pre-eclampsia Screening in China
NCT05445544 ·Status: RECRUITING