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Real Life Study of Biologicals in Patients With Severe CRSwNP

NCT05938972 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2024-04-15

No results posted yet for this study

Summary

This study is a pragmatic, real-life, observational study recruiting adult patients with chronic rhinosinusitis with nasal polyposis who are eligible to start biologicals as standard treatment. The aim of this study is to observe the long-term outcomes of biologicals in CRSwNP patients with or without comorbid asthma in 'real life'. Moreover, the investigators will gain insight into the mechanisms of biologicals in the local and systemic immunity of these patients and investigate novel local and systemic biomarkers and predictors of response.

Conditions

Interventions

BIOLOGICAL

Mepolizumab

Monoclonal antibodies

Sponsors & Collaborators

  • University Hospital, Ghent

    lead OTHER

Principal Investigators

  • Philippe Gevaert, Prof. Dr. · University Hospital, Ghent

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-01
Primary Completion
2030-12-31
Completion
2030-12-31

Countries

  • Belgium

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05938972 on ClinicalTrials.gov