Translational-Omics in Aortic Stenosis (TOmAS) Biobank
NCT05930899 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 10000
Last updated 2024-11-20
Summary
The objective of the TOmAS Biobank is the conservation of biological material (plasma, saliva, and tissue explanted during surgery), genetic material (DNA, RNA, etc.), and clinical data ("material/data") collected from patients with cardiovascular diseases (CVD) as well as from control participants, in order to allow future studies evaluating novel proteomic, transcriptomic and epigenomic markers (as well as other emerging -omic technologies) for CVD (i.e. aortic stenosis, cardiomyopathy, myorcardial infarction, etc). The study of physiological and genetic factors will allow for the discovery of new genomic and other -omic (including proteomic, transcriptomic and epigenomic) biomarkers associated with CVD which will lead to an improved understanding of the underlying biology of CVD and may provide future insights into the prevention and treatment of this type of disease.
Conditions
- Cardiovascular Diseases
- Aortic Valve Stenosis
Interventions
- OTHER
-
Genetics
TOmAS is a biobank and all patients will be genotyped
Sponsors & Collaborators
-
McGill University Health Centre/Research Institute of the McGill University Health Centre
lead OTHER
Eligibility
- Min Age
- 19 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-10-12
- Primary Completion
- 2040-01-01
- Completion
- 2040-01-01
Countries
- Canada
Study Locations
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