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Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial

NCT05924477 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 226

Last updated 2025-06-27

No results posted yet for this study

Summary

Glaucoma Drainage Device and Endothelial Cell Loss Compare Trial (DECLARE) is a multi-center, outcome-masked, randomized clinical trial. The purpose of this study is to compare glaucoma drainage device implantation in the anterior chamber (front part of the eye) and sulcus (small space between iris and front chamber of the eye) in efforts to minimize cell loss in the eye.

Conditions

Interventions

PROCEDURE

Sulcus tube placement

GDD implantation surgery with tube placement in the ciliary sulcus

PROCEDURE

Anterior chamber (AC) tube placement

GDD implantation surgery with tube placement in the anterior chamber

Sponsors & Collaborators

Principal Investigators

  • Ying Han, MD, PhD · University of California, San Francisco

  • Jennifer Rose-Nussbaumer, MD · Stanford University

  • Thuy Doan, MD, PhD · University of California San Fransicso

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-11
Primary Completion
2026-12-31
Completion
2027-12-31

Countries

  • United States
  • Canada

Study Locations

More Related Trials

Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05924477 on ClinicalTrials.gov