Flexible Reaching Control in Parkinson Disease

NCT05908266 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2023-06-18

No results posted yet for this study

Summary

Current research and theories have highlighted that the parameters linked to movement planning, e.g. the decision to select a movement goal, and adaptation, e.g. the ability to update control dependent on a novel dynamical context, are update quickly and within an ongoing movement in the general population. In parallel, it has been suggested that the evaluation of movement costs is a function of the basal ganglia, and it is impaired in Parkinson disease (PD). Here the investigators want to test whether these mechanisms also alter the ability of patients to update control during an ongoing action. A positive result would confirm that movement-related costs and dynamical representations depend on the integrity of the basal ganglia, in contrast a negative result would indicate that the deficit in PD is more specifically related to movement initiation, which would invite one to reconsider the cause of bradykinesia in this population.

Conditions

  • Parkinson Disease

Interventions

OTHER

Reaching movements

Participants will be instructed to perform reaching movements by moving the handle of a robotic arm mounted with a virtual reality display.

OTHER

Disease Assessment

Disease stage assessed by trained professionals

Sponsors & Collaborators

  • Université Catholique de Louvain

    lead OTHER

Principal Investigators

  • Frédéric Crevecoeur, PhD · Université Catholique de Louvain

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-05-01
Primary Completion
2027-10-31
Completion
2027-10-31

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05908266 on ClinicalTrials.gov