Flexible Reaching Control in Parkinson Disease
NCT05908266 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2023-06-18
Summary
Current research and theories have highlighted that the parameters linked to movement planning, e.g. the decision to select a movement goal, and adaptation, e.g. the ability to update control dependent on a novel dynamical context, are update quickly and within an ongoing movement in the general population. In parallel, it has been suggested that the evaluation of movement costs is a function of the basal ganglia, and it is impaired in Parkinson disease (PD). Here the investigators want to test whether these mechanisms also alter the ability of patients to update control during an ongoing action. A positive result would confirm that movement-related costs and dynamical representations depend on the integrity of the basal ganglia, in contrast a negative result would indicate that the deficit in PD is more specifically related to movement initiation, which would invite one to reconsider the cause of bradykinesia in this population.
Conditions
- Parkinson Disease
Interventions
- OTHER
-
Reaching movements
Participants will be instructed to perform reaching movements by moving the handle of a robotic arm mounted with a virtual reality display.
- OTHER
-
Disease Assessment
Disease stage assessed by trained professionals
Sponsors & Collaborators
-
Université Catholique de Louvain
lead OTHER
Principal Investigators
-
Frédéric Crevecoeur, PhD · Université Catholique de Louvain
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-05-01
- Primary Completion
- 2027-10-31
- Completion
- 2027-10-31
Countries
- Belgium
Study Locations
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