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Investigating Neural Biomarkers for Gait in Parkinson's Patients

NCT05820074 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2024-12-03

No results posted yet for this study

Summary

This observational study's main goal is to learn more about the neural mechanisms during movement in Parkinson's disease. Furthermore, it aims to inspire personalised treatment options.

Participants will undergo a protocol that involves walking and gait-related motor tasks, such as seated stepping. During the protocol, brain activity will be recorded.

Conditions

  • Parkinson Disease
  • Gait Disorders, Neurologic

Interventions

DIAGNOSTIC_TEST

Neural Activity Recording

Neural Activity is measured using EEG in all groups. Additionally, in Parkinson's patients, local-field-potentials from deep brain stimulation electrodes are recorded.

DIAGNOSTIC_TEST

Movement Parameter Recording

Gait-related movement parameters are non-invasively recorded using motion capture, accelerometers and electromyography.

OTHER

Neuromodulation

Neural signals are recorded with the electrodes of the deep brain stimulation device. Parkinson's patients are asked to modulate their neural activity by observing the streamed neural activity and applying mental strategies.

Sponsors & Collaborators

  • cereneo center for Neurology and Rehabilitation

    collaborator UNKNOWN

  • University of Zurich

    collaborator OTHER

  • Swiss Federal Institute of Technology

    lead OTHER

Principal Investigators

  • Olivier Lambercy, PhD · RELab, ETH Zürich

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-13
Primary Completion
2025-03-31
Completion
2025-03-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05820074 on ClinicalTrials.gov