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Propofol or Sevoflurane Anesthesia in Egyptian Patients

NCT05289349 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 44

Last updated 2024-06-04

No results posted yet for this study

Summary

The proposed research in this application will investigate postoperative cognitive function, pain index, inflammatory response, and oxidative stress effects of propofol versus sevoflurane anesthetic drugs in patients undergoing elective, non-cardiac abdominal operations under general anesthesia to investigate which of them will significantly maintain better cognitive function, decrease the pain index, inflammatory reaction, and oxidative stress, improve outcome, shorten the postoperative recovery time and reduce length of hospital stay, and consequently the cost of hospital stay.

Conditions

  • Anesthesia

Interventions

DRUG

Propofol

Propofol (2 mg/kg) for induction of anesthesia , and ( 6 mg/kg/h) for maintenance of anesthesia

DRUG

Sevoflurane

Sevoflurane 1.0-1.5 minimum alveolar concentration (MAC)

Sponsors & Collaborators

  • Rehab Werida

    lead OTHER

Principal Investigators

  • Rehab H Werida, Ass Prof. · Damanhour University

  • Amira Kassem, Ph.D · Damanhour University

  • Ahmed Shaat, Ph.D. · Damanhour Teaching Hospital

  • Heba Elwan · Damanhour University

  • Ahmad Salahuddin, Ph.D · Damanhour University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-12-01
Primary Completion
2023-03-31
Completion
2023-04-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05289349 on ClinicalTrials.gov