Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in Chinese Adults Who Are Above a Healthy Weight Range (OASIS 3)
NCT05890976 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 200
Last updated 2026-01-22
Summary
This study is being conducted to see if semaglutide tablets can be used as a treatment to help people who are above a healthy weight range to lose weight. Semaglutide tablets are a new medicine being tested to treat people living with excess body weight. Participants will either get semaglutide or placebo once daily morning for 44 weeks.
In addition to taking the medicine, participants will have talks with study staff about:
* Healthy food choices
* How to be more physically active
* What participants can do to lose weight This study will last for about 1 year.
Conditions
Interventions
- DRUG
-
Participants will receive semaglutide tablets orally once daily for 44 weeks.
- DRUG
-
Semaglutide Placebo
Participants will receive placebo matched to semaglutide.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Clinical Transparency (dept. 2834) · Novo Nordisk A/S
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-30
- Primary Completion
- 2025-01-16
- Completion
- 2025-01-16
- FDA Drug
- Yes
Countries
- China
Study Locations
More Related Trials
-
A Research Study Looking at How 50 mg Semaglutide Daily Affects Food Intake and Emptying of the Stomach in People With Obesity
NCT05236517 ·Status: COMPLETED ·Phase: PHASE1
-
Research Study Looking at How Well Semaglutide Tablets Taken Once Daily Work in People Who Have a Body Weight Above the Healthy Range
NCT05564117 ·Status: COMPLETED ·Phase: PHASE3
-
STEP 6: Research Study Investigating How Well Semaglutide Works in People Living With Overweight or Obesity
NCT03811574 ·Status: COMPLETED ·Phase: PHASE3
-
Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
NCT03548987 ·Status: COMPLETED ·Phase: PHASE3
-
The Effect of Weekly Semaglutide Treatment on Energy Expenditure
NCT06390501 ·Status: COMPLETED ·Phase: NA
-
Research Study Investigating How Well Semaglutide Works in People From Thailand and South Korea Living With Obesity
NCT04998136 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial to Assess the Pharmacokinetics, Safety and Tolerability of Semaglutide in Healthy Chinese Subjects
NCT03288740 ·Status: COMPLETED ·Phase: PHASE1
-
Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
NCT05040971 ·Status: COMPLETED ·Phase: PHASE3
-
Research Study Investigating How Well Semaglutide Works in People With Type 2 Diabetes Suffering From Overweight or Obesity
NCT03552757 ·Status: COMPLETED ·Phase: PHASE3
-
A Research Study Comparing a New Medicine Oral Semaglutide to Placebo in People With Type 2 Diabetes
NCT04109547 ·Status: COMPLETED ·Phase: PHASE3
-
Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes Mellitus
NCT02453711 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of TG103 Injection in Non-diabetic Overweight or Obesity
NCT05997576 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of HS-20094 in Chinese Adults with Overweight or Obesity
NCT06839664 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of the Efficacy and Safety of Semaglutide Injection in the Treatment of Type 2 Diabetes Mellitus
NCT05816057 ·Status: COMPLETED ·Phase: PHASE3
-
Semaglutide's Weight Loss Effects in Obesity
NCT06825793 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
A Study to Compare XW003 Injection and Semaglutide Injection in Chinese Adults With Obesity (SLIMMER-UP-SWITCH)
NCT07073417 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Efficacy and Safety of Semaglutide Ingection in Subjects With Type 2 Diabetes
NCT05950516 ·Status: UNKNOWN ·Phase: PHASE3
-
A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants After 10 Days of Oral Dosing
NCT06820476 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy of Oral Semaglutide in Overweight or Obesity
NCT05442450 ·Status: UNKNOWN ·Phase: PHASE4
-
Two-year Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
NCT03693430 ·Status: COMPLETED ·Phase: PHASE3
-
STEP 1: Research Study Investigating How Well Semaglutide Works in People Suffering From Overweight or Obesity
NCT03548935 ·Status: COMPLETED ·Phase: PHASE3
-
A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Chinese Men
NCT05498610 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASC47 in Combination With Semaglutide
NCT06972992 ·Status: COMPLETED ·Phase: PHASE1
-
Efficacy and Safety of Semaglutide Injection Vs WEGOVY® in Chinese Obese Patients
NCT07036172 ·Status: RECRUITING ·Phase: PHASE3
-
Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.
NCT05419726 ·Status: RECRUITING