Engineering Immune Organoids to Study Pediatric Cancer
NCT05890781 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 108
Last updated 2026-02-09
Summary
To engineer immune organoids from pediatric patient tissues using induced-pluripotent stem cells (iPSC)
Conditions
- Brain Tumor
- Kidney Tumor
- Neuroblastoma
- Sarcoma
Interventions
- PROCEDURE
-
Spinal cerebrospinal fluid (SCF)
Spinal cerebrospinal fluid (SCF) whenever possible
- PROCEDURE
-
Skin biopsy
Skin biopsy
- PROCEDURE
-
Fresh tumor sample
Fresh tumor sample
- BIOLOGICAL
-
Blood sample
Blood sample in heparin tubes (highly recommended), to be collected before starting treatment or as soon as hematological recovery has been reached
- PROCEDURE
-
Healthy tissue from the tumor
Healthy tissue from the tumor site whenever possible
Sponsors & Collaborators
-
Gustave Roussy, Cancer Campus, Grand Paris
lead OTHER
Study Design
- Allocation
- NA
- Purpose
- OTHER
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Max Age
- 25 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-05-12
- Primary Completion
- 2028-05-31
- Completion
- 2028-05-31
Countries
- France
Study Locations
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