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Low-dose Contrast Media for Low-kVp Abdomen CT

NCT05878665 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 292

Last updated 2025-05-28

No results posted yet for this study

Summary

The purpose of this clinical study is to test the performance of low radiation dose abdominal CT combined with low dose contrast media for the diagnosis of acute appendicitis in young patients. The main questions to be answered are:

1, Can low-dose contrast media paired with low-dose radiation CT of the abdomen provide acceptable diagnostic accuracy in acute appendicitis? 2. How much radiation dose can be saved by using low radiation dose abdominal CT in combination with low dose contrast media?

Conditions

  • Appendicitis Acute

Interventions

DIAGNOSTIC_TEST

Weight-adjusted low-dose contrast media paired with low-radiation dose abdomen CT

The investigators are aiming for a 10% reduction in iodine dosage at 10 kVp reduction in CT radiation. Routine iodine dosing is 0.521 g I/kg at 120 kVp. Therefore, at 90 kVp, a 30% reduction in iodine dosing is expected, which is 0.365 g I/kg. At 100 kVp, the iodine dosage is reduced to 0.417 g I/kg, which is a 20% reduction. The kVp value is automatically selected by the CT device according to the body habitus, which is a clinical routine.

Sponsors & Collaborators

  • GE Healthcare

    collaborator INDUSTRY

  • Bohyun Kim

    lead OTHER

Principal Investigators

  • Bohyun Kim, MD, PhD · Seoul St. Mary's Hospital

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
19 Years
Max Age
44 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-12-21
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05878665 on ClinicalTrials.gov