CT DOSE Collaboratory

Summary

This is a pragmatic stepped-wedge cluster randomized controlled trial to explore variation in doses used for diagnostic CT by pooling radiation dose data across diverse healthcare delivery systems.

To compare different strategies for lowering and optimizing dose and identify the barriers and facilitators to implementing successful dose optimization strategies and standardizing practice.

Conditions

• Ionizing Radiation Exposure
• Quality Improvement

Interventions

OTHER

Simple Audit Report

The simple audit provides comparison and feedback on radiation doses.

OTHER

Multi-Component Intervention

The multi-component intervention gives tailored feedback on needed changes plus guidance using quality improvement methods that facilitate organizational change. Provides access to experts, detailed audit, collaborative calls, and site visits (as needed).

OTHER

In-Person Meeting

Collaborator meeting with an emphasis on quality improvement.

Sponsors & Collaborators

• University of California, Davis

  collaborator OTHER

• University Hospital, Basel, Switzerland

  collaborator OTHER

• Center for Diagnostic Imaging

  collaborator OTHER

• Community Health Network

  collaborator OTHER

• Children's Mercy Hospital Kansas City

  collaborator OTHER

• City of Hope Medical Center

  collaborator OTHER

• Albert Einstein Healthcare Network

  collaborator OTHER

• Universität Duisburg-Essen

  collaborator OTHER

• East Texas Medical Center Regional Healthcare System

  collaborator OTHER

• Emory University

  collaborator OTHER

• Henry Ford Health System

  collaborator OTHER

• Huntsville Hospital Health System

  collaborator OTHER

• Nicklaus Children's Hospital f/k/a Miami Children's Hospital

  collaborator OTHER

• Mount Sinai Hospital, New York

  collaborator OTHER

• Maastricht University Medical Center

  collaborator OTHER

• Olive View-UCLA Education & Research Institute

  collaborator OTHER

• Oxford University Hospitals NHS Trust

  collaborator OTHER

• San Francisco VA Health Care System

  collaborator FED

• St. Joseph Hospital of Orange

  collaborator OTHER

• St. Luke's International Hospital, Japan

  collaborator OTHER

• University of Virginia

  collaborator OTHER

• University of California, Irvine

  collaborator OTHER

• University of California, San Diego

  collaborator OTHER

• National Cancer Institute (NCI)

  collaborator NIH

• University of California, San Francisco

  lead OTHER

Principal Investigators

• Rebecca Smith-Bindman, MD · University of California, San Francisco

• Judy Yee, MD · San Francisco Veterans Administration

• Tom Nelson, PhD · University of California, San Diego

• Tony Seibert, PhD · University of California, Davis

• Mayil Krishnam, MD · University of California, Irvine

• Michael Flynn, PhD · Henry Ford Health System

• Mary Cocker, MSc, Csci · Oxford University Hospitals NHS Trust

• William Boswell, MD · City of Hope Medical Center

• Sebastian Schindera, MD · University Hospital of Basel

• Erin Bell, MHP · Community Health Network

• Phuong-Anh Duong, MD · Emory University

• Nima Kasraie, PhD, MSc · Children's Mercy Hospital Kansas City

• Pavlina Pike, PhD · Huntsville Hospital

• Luisa Cervantes, MD · Nicklaus Children's Hospital f/k/a Miami Children's Hospital

• Joachim Wildberger, PhD · Maastricht University Medical Center

• Michael Forsting, MD · University of Duisburg-Essen

• Fady Kassem, PhD · St. Joseph Hospital of Orange

• Darrell Fendrick, CT · East Texas Medical Center

• Sugoto Mukherjee, MD · University of Virginia Health System

• Brad Delman, MD · Icahn School of Medicine at Mount Sinai

• Jodi Roehm · Center for Diagnostic Imaging

• Anokh Pahwa, MD · Olive View - UCLA

• Ryan Lee, MD, MBA · Einstein Medical Center

• Jay Starkey, MD · St. Luke's International Hospital, Tokyo

• Diana Miglioretti, PhD · University of California, Davis

• Saravanabavaan Suntharalingam, MD · University of Duisburg-Essen

• Sara Lewis, MD · Icahn School of Medicine at Mount Sinai

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

FACTORIAL

Eligibility

Max Age

99 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2016-07-31

Primary Completion

2020-12-31

Completion

2020-12-31