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Cementless Triathlon 5YR Follow-Up

NCT05877261 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 18

Last updated 2025-03-17

No results posted yet for this study

Summary

All artificial joint implants need to be solidly held (fixed) within the bone. Cementless fixation has become a popular method to achieve fixation for total knee replacements where the bone grows directly onto the implanted device instead of using bone cement. The primary purpose of this study is to assess long-term implant survivorship and clinical outcomes of a previous study cohort that received a cementless knee replacement. As this study cohort approaches 5 years post-operation, the investigators will re-examine the stability of participant implants using specialized x-rays, called "radiostereometric analysis". The study will use weight-bearing computed tomography (CT) to measure bone density and texture features and correlate that with implant stability. The investigators will collect stool samples to assess participant gut microbiomes for biomarkers of poor bone quality that could correlate to implant stability. All 33 participants from the original study cohort will be invited to participate in this study.

Conditions

Interventions

DEVICE

Cementless Total Knee Replacement

Artificial knee implant inserted by cementless fixation.

Sponsors & Collaborators

  • Schulich School of Medicine and Dentistry

    collaborator UNKNOWN

  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

    lead OTHER

Principal Investigators

  • Brent Lanting, MD MSc FRCSC · Schulich School of Medicine and Dentistry

Eligibility

Min Age
21 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-05-25
Primary Completion
2024-04-01
Completion
2024-12-31

Countries

  • Canada

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05877261 on ClinicalTrials.gov