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The Influence of Daily Grapes Intake on Sarcopenia in Postmenopausal Women

NCT05863507 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 15

Last updated 2024-11-12

No results posted yet for this study

Summary

Sarcopenia, characterized by loss of muscle mass and function, is a prevalent disorder in elderly individuals or individuals with chronic diseases. Given the above, there is an ongoing intensive search for novel therapies, including dietary ones, that can attenuate the loss of muscle mass and strength in the elderly. A proposed mechanism by which skeletal muscles might mediate their protective effect against sarcopenia is by secreting myokines as irisin. Phenolic compounds presents in grape have shown to be able to induce irisin secretion in muscle from rats supplemented with a grape pomace extract. The Ian of this study is to evaluate this mechanism in humans.

Conditions

Interventions

DIETARY_SUPPLEMENT

Grape powder supplementation

The participants will be willing to consume the grape powder dissolve in water daily for 6 weeks

DIETARY_SUPPLEMENT

Placebo

The participants will be willing to consume the placebo powder, similar to the grape powder, dissolve in water daily for 6 weeks

Sponsors & Collaborators

  • California Table Grape Commission

    collaborator OTHER

  • University of California, Davis

    lead OTHER

Principal Investigators

  • Francene G Steinberg, PhD · University of California, Davis

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2024-07-14
Completion
2024-07-14

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05863507 on ClinicalTrials.gov