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Maternal Choline Supplementation and Offspring Cognition in Adolescence

NCT05859126 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 26

Last updated 2024-08-22

No results posted yet for this study

Summary

The goal of this 13-year follow up of a randomized control trial is to study the effect of maternal choline supplementation on offspring cognition in adolescence.

The main question\[s\] it aims to answer are:

Does a higher dose of maternal choline choline (930 mg/d day supplementation) lead to improved cognition in adolescence including hippocampal-dependent episodic memory and executive functioning when compared to lower dose supplementation (480 mg/d).

In this follow-up of a clinical trial participants will complete online cognition testing and emotion testing.

Conditions

  • Cognitive Deficit in Attention
  • Executive Dysfunction
  • Emotional Regulation

Interventions

DIETARY_SUPPLEMENT

Maternal Choline Supplementation 930 mg/d

Mothers were supplemented with choline (930mg/d) from second trimester through birth. This is a 13 year follow up of their offspring.

DIETARY_SUPPLEMENT

Maternal Choline Supplementation 480 mg/d

Mothers were supplemented with choline (480 mg/d) from second trimester through birth. This is a 13 year follow up of their offspring.

Sponsors & Collaborators

Principal Investigators

  • Barbara Strupp, PhD · Cornell University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
13 Years
Max Age
13 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-06-23
Primary Completion
2024-10-31
Completion
2024-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05859126 on ClinicalTrials.gov