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Chronic Inflammation and Exercise Responsiveness

NCT02732509 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 146

Last updated 2022-01-13

No results posted yet for this study

Summary

The purpose of this study is to determine how chronic inflammation influences skeletal muscle protein metabolism and metabolic function in humans. The investigators will evaluate acute responsiveness to a single bout of exercise in men and women who are either lean or overweight/obese. The investigators will explore the relationship between circulating inflammatory markers and anabolic, proteomic, and transcriptional responses to acute exercise. The investigators will measure skeletal muscle protein synthesis in the postabsorptive state and in response to a single bout of exercise.

Conditions

  • Metabolic Syndrome

Sponsors & Collaborators

Principal Investigators

  • Ian R Lanza, PhD · Mayo Clinic

Eligibility

Min Age
30 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2021-12-31
Completion
2021-12-31

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02732509 on ClinicalTrials.gov