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The Effects of Allicor on Patients After Revascularization Treatment During a Year

NCT05813171 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2023-04-19

No results posted yet for this study

Summary

A significant challenge in medical care is atherosclerotic occlusion of peripheral arteries, such as lower extremities and brachiocephalic arteries, which can eventually lead to loss of limbs or fatal ischemic strokes. Revascularizing surgical interventions can restore the lumen of the arteries and provide an effective way to treat such patients. However, up to a third of patients need re-intervention or experience cardiovascular complications within a year after surgery. The purpose of this study is to evaluate the effect of adding the natural dietary supplement Allicor to conventional treatment on the incidence of cardiovascular complications and treatment effectiveness 12 months after revascularization. Another valuable area of investigation is the search for predictors of long-term cardiovascular complications after revascularization, which could be markers of inflammation and heteroplasmy levels in the patient's mitochondrial genome.

Conditions

Interventions

DIETARY_SUPPLEMENT

Allicor

Participants will take Allicor capsules in addition to standard treatment for a year.

DRUG

Placebo

Participants will take the placebo capsules in addition to standard treatment for a year.

Sponsors & Collaborators

  • Institute for Atherosclerosis Research, Russia

    lead OTHER

Principal Investigators

  • Nikolay K Shakhpazyan, PhD; Dr. · "Russian research center of surgery named after academician B.V. Petrovsky"

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-04-20
Primary Completion
2024-04-20
Completion
2024-05-31

Countries

  • Russia

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05813171 on ClinicalTrials.gov