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Exercise Induced Plasma Volume Expansion Lowers Cardiovascular Strain

NCT05800808 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2023-04-06

No results posted yet for this study

Summary

The goal of this observational study was to better understand the impact of increased plasma volume on later exercise in hypoxia. Investigators examined young, healthy, males who regularly participated in aerobic exercise.

Investigators first measured participant's response to exercise in hypoxia (simulated \~7,500 feet above sea level). The investigators then had participants either 1) undergo 1 bout of high intensity interval exercise or 2) undergo 1 bout of moderate, continuous exercise.

48 hours after the exercise, participants were again examined in hypoxia.

Conditions

  • Cardiac Output
  • Stroke Volume

Interventions

PROCEDURE

High Intensity Intervals

8x4 min cycling bouts at 85% of VO2peak

PROCEDURE

Moderate Exercise

81 minutes of cycling at 50% VO2peak

Sponsors & Collaborators

  • High Point University

    collaborator OTHER

  • United States Army Research Institute of Environmental Medicine

    collaborator FED

  • California Baptist University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
38 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2019-01-15
Primary Completion
2019-12-15
Completion
2022-12-08

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05800808 on ClinicalTrials.gov