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Effect of Inhalation of Low Dose CO2 on Exercise Performance at High Altitude

NCT05798416 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 28

Last updated 2023-05-18

No results posted yet for this study

Summary

High altitude (\>2400 m) is associated with decreased atmosphere pressure leading to hypoxia which in turn impairs exercise capacity and causes acute mountain sickness (AMS). It is noted that adding CO2 might be beneficial to improve hypoxia and exercise performance at high altitude. However, no device is currently available that can supply a constant low dose of CO2 during free movement at high altitude. We have recently invented a portable device which is small and light enough for supplement of low dose CO2 during field exercise at high altitude.

Conditions

  • High Altitude
  • Inhalation; Gas
  • Acute Mountain Sickness

Interventions

DRUG

Exercise under inhalation CO2

Participants perform shuttle walk test at high altitude while using the novel portable device for inhalation of CO2

OTHER

Exercise under inhalation ambient air

Participants perform shuttle walk test at high altitude while inhaling ambient air

Sponsors & Collaborators

  • State Key Laboratory of Respiratory Disease

    lead OTHER

Principal Investigators

  • Yuanming Luo, PhD · The Affiliated Hospital og Guangzhou Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-02-15
Primary Completion
2023-04-15
Completion
2023-04-29

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05798416 on ClinicalTrials.gov