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Effect of Rehabilitation on the Respiratory Signal in Patients With COPD and Exercise-Induced Desaturation

NCT07107828 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 52

Last updated 2025-08-06

No results posted yet for this study

Summary

The aim is to study the effect of SSOT during a 3-week in-patient pulmonary rehabilitation programme. Further aim is to analyse exercise endurance, distinguishing between those exercising whilst breathing air at 760m "normoxia", breathing air at 1600m "hypoxia", or breathing SSOT at 760m "hyperoxia" conditions, during in-patient pulmonary rehabilitation.

The objective of the main study is to provide long-awaited data concerning the use of SSOT during training. At present it is unclear whether patients with chronic lung diseases who reveal an SpO2 \> 88% at rest, but desaturate during exercise, and, thus, may not qualify for long-term oxygen undergoing PR benefit from supplemental oxygen.

This sub-study will involve the subjects wearing the Respeck device and will focus on the effect of exercise on the respiratory signal measured by the Respeck.

Conditions

  • COPD (Chronic Obstructive Pulmonary Disease)

Interventions

OTHER

Ambient air

Standard ambient air will be breathed during endurance training.

OTHER

Oxygen

SSOT will be applied during endurance training

OTHER

Altitude

Training will be performed at moderate altitude

Sponsors & Collaborators

  • University of Edinburgh

    collaborator OTHER

  • National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov

    collaborator OTHER_GOV

  • Eastern Switzerland University of Applied Sciences

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
SEQUENTIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-07-23
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Kyrgyzstan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07107828 on ClinicalTrials.gov