The Association Between SIRI and POD in Older Patients
NCT05797194 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 116
Last updated 2023-04-04
Summary
Postoperative delirium (POD) remains one of most common complication in elderly patients receiving surgery, which is characterized by acute and fluctuating change in the level of cognition and consciousness. Previous studies have shown that surgery and anesthesia-induced acute peripheral inflammation and neuroinflammation may lead to delirium after surgery. Systemic Inflammation Response Index (SIRI) is a more easily accessible and comprehensive inflammation marker derived from monocyte, neutrophil, and lymphocyte count, which has been investigated to assess the prognosis of cancer and infectious diseases. However, the relationship between SIRI and POD has yet to be investigated.
Conditions
- Postoperative Delirium
- Elderly
- Surgery
Sponsors & Collaborators
-
Changhai Hospital
lead OTHER
Eligibility
- Min Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2019-03-01
- Primary Completion
- 2019-10-31
- Completion
- 2019-10-31
Countries
- China
Study Locations
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