COMPARISON OF DEXMEDETOMIDINE AND REMIFENTANIL FOR POSTOPERATIVE PAIN IN TRANSPHENOIDAL Pituitary SURGERY
NCT05772832 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 104
Last updated 2025-08-27
Summary
In patients with pituitary adenoma scheduled for endoscopic transsphenoidal pituitary surgery, it was aimed to compare the efficacy of postoperative pain relief of a selective α-2 agonist "Dexmedetomidine" and the rapid and short-acting opioid "Remifentanil" using the "Numerical Rating Scale" (NRS) administered alongside propofol in perioperative maintenance anesthesia. .
Conditions
- Postoperative Pain
Interventions
- DRUG
-
Dexmedetomidine
Efficacy of dexmedetomidine on postoperative pain in patients undergoing transsphenoidal pituitary surgery
- DRUG
-
Remifentanyl
Efficacy of remifentanyl on postoperative pain in patients undergoing transsphenoidal pituitary surgery
Sponsors & Collaborators
-
Kocaeli University
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-11-17
- Primary Completion
- 2022-12-14
- Completion
- 2023-02-22
- FDA Drug
- Yes
Countries
- Turkey (Türkiye)
Study Locations
More Related Trials
-
Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
NCT06138574 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Sphenopalatine Block vs Dexmedetomidine Infusion in Trans Nasal Endoscopic Pituitary Surgery
NCT06639659 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
EFFECT OF DEXMEDETOMİDİNE ON RECURRENT LARYNGEAL NERVE MONİTORİNG: A COMPARATİVE STUDY WİTH MİDAZOLAM
NCT07195214 ·Status: COMPLETED
-
Effect of Dexmedetomidine on Quality of Recovery in Non-functioning Pituitary Adenoma Patients Undergoing Endoscopic Transsphenoidal Surgery
NCT05005715 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy of Remifentanil in Preventing Emergence Agitation
NCT06539013 ·Status: RECRUITING ·Phase: NA
-
Dexmedetomidine vs. Remifentanil Undergoing Cataract Surgery in Geriatrics
NCT04935541 ·Status: COMPLETED ·Phase: NA
-
Comparison of Dexmedetomidin and Remifentanil for the Effect on Airway Reflex and Hemodynamic Response During Emergence in Patients Undergoing Craniotomy
NCT01365923 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Dexmedetomidine on Stress Study of Pituitrin in Laparoscopic Hysteromyoma Surgery
NCT03524950 ·Status: UNKNOWN ·Phase: PHASE3
-
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Dental Treatment
NCT06097169 ·Status: COMPLETED
-
Dexmedetomidine and Remifentanil in NORA
NCT06403670 ·Status: COMPLETED ·Phase: PHASE4
-
A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain
NCT01269918 ·Status: COMPLETED ·Phase: NA
-
Effect of Dexmedetomidine on Nol-Index Guided Remifentanil Analgesia
NCT03912740 ·Status: COMPLETED ·Phase: NA
-
Antitussive Effect of Single-dose Dexmedetomidine With Low-dose Remifentanil Infusion
NCT02208505 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Remifentanil and Dexmedetomidine for Monitored Anaesthesia Care During Vertebroplasty and Kyphoplasty
NCT02476981 ·Status: COMPLETED ·Phase: NA
-
Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of Postoperative Shivering After General Anaesthesia for Abdominal Surgeries
NCT07154849 ·Status: RECRUITING ·Phase: PHASE4
-
Dexmedetomidine Infusion During Laparoscopic Adrenalectomy
NCT06037135 ·Status: COMPLETED ·Phase: NA
-
Intrathecal Versus Intravenous Dexmedetomidine in Prostate Transurethral Resection
NCT05525819 ·Status: UNKNOWN ·Phase: NA
-
Dexmedetomidine Premedication in Hypertensive Patients
NCT02058485 ·Status: COMPLETED ·Phase: PHASE3
-
Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy
NCT04607525 ·Status: COMPLETED ·Phase: PHASE4
-
Dexmedetomidine and Desflurane Consumption
NCT02652312 ·Status: COMPLETED ·Phase: NA
-
The Effect of Dexamethasone on Rebound Pain in Patients Receiving Ilioinguinal and Iliohypogastric Nerve Block
NCT05172908 ·Status: COMPLETED ·Phase: NA
-
Evaluation of the Postoperative Agitation Prevention and Analgesic Efficacy of Perioperative Dexmedetomidine Infusion in a Pediatric Patient Group to Undergo Tonsillectomy and Adenoidectomy
NCT05986942 ·Status: COMPLETED
-
Effect of Dexmedetomidine After Thyroidectomy
NCT02412150 ·Status: COMPLETED ·Phase: NA
-
Effects Of Propofol-Dexmedetomıdıne And Propofol- Remıfentanıl In Hysteroscopıc Operations.
NCT05674201 ·Status: COMPLETED
-
Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine for Intermediate Cervical Plexus Block
NCT05793060 ·Status: RECRUITING ·Phase: PHASE4