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Dexmedetomidine and Desflurane Consumption

NCT02652312 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2016-11-10

No results posted yet for this study

Summary

The aim of this study is to calculate desflurane consumption when combined with intraoperative dexmedetomidine infusion guided by bispectral index (BIS)

Conditions

  • Anesthesia

Interventions

DRUG

Dexmedetomidine

A maintenance dose of Dexmedetomidine infusion at 0.5 mcg/kg/hour made to 20 mL with normal saline will be administered

DRUG

Placebo

A maintenance dose of 20 mL with normal saline will be administered at a rate similar to that of dexmedetomidine

PROCEDURE

Ondansetron

0.15 mg/kg intravenous (IV) will be given as a pre-medication

PROCEDURE

fentanyl

1.5 μg/kg intraoperative

PROCEDURE

propofol

10 mg every 5 seconds until the BIS level dropped below 60 for induction of anesthesia

PROCEDURE

Atracurium

0.5 mg/kg IV for endotracheal intubation

PROCEDURE

diclofenac sodium

1 mg/kg for postoperative analgesia

PROCEDURE

desflurane

1 MAC concentration (expired fraction of 6.0 vol%) for maintenance of anesthesia

Sponsors & Collaborators

  • Theodor Bilharz Research Institute

    lead OTHER

Principal Investigators

  • Abla El Hadidy, PhD · Theodor Bilharz Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
15 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-02-29
Primary Completion
2016-10-31
Completion
2016-10-31

Countries

  • Egypt

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02652312 on ClinicalTrials.gov