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The Effect of Multiple Injections of (PRF) on The Rate of Canine Retraction

NCT05766618 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 22

Last updated 2023-03-13

No results posted yet for this study

Summary

this clinical trial aims to prove that multiple injections will produce a steady rate of acceleration of orthodontic tooth movement.

Conditions

  • Platelet-Rich Fibrin
  • Acceleration
  • Orthodontics

Interventions

PROCEDURE

Injectable platelet rich fibrin (i-PRF): in acceleration of orthodontic tooth movement

Preparatory phase * Space closure will be done on a 17x25 stainless steel wire * Both molars will be indirectly anchored to the miniscrew * Extend closing coil spring of suitable length from the canine hock to the first molar hock for retraction. * Apply a force of 150gm for each side. The force is measured by a force gauge and activated each visit to keep it constant all over the retraction phase. PRF Injection protocol * The First injection will be 3 weeks before extraction * By the end of the fourth week the patients will be referred for pre-intervention records. Upper arch CBCT will be obtained to take preintervention measurements of the alveolar bone. * At the time of canine retraction patient will receive another injection immediately and an alginate impression will be taken * follow up every month and injection will be repeated month after month with an observational period of 5 months.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Mohamed M Alkhawaga, BDS · Cairo University

  • Fady Fahim, phD · Cairo University

  • Sally Magdy, phD · Cairo University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
16 Years
Max Age
24 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-04-01
Primary Completion
2024-06-01
Completion
2024-10-01

Countries

  • Egypt

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05766618 on ClinicalTrials.gov