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SPEECH as Biomarker for Emotion, Movement and cOgnition in Parkinson's Disease

NCT05765110 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-05-22

No results posted yet for this study

Summary

With this study, the investigators want to investigate whether computerized speech analysis can be used to reliably and objectively detect motor, emotional, and cognitive fluctuations in Parkinson's disease patients.

Conditions

  • Parkinson Disease

Interventions

OTHER

Dopaminergic OFF drug state

Experiment will be performed without dopaminergic medication

OTHER

DBS OFF state

Turning off the stimulation during experiment

OTHER

Dopaminergic ON drug state

Experiment will be performed with dopaminergic medication

OTHER

DBS ON state

Experiment will be performed with stimulation (ON condition)

Sponsors & Collaborators

  • Czech Technical University in Prague

    collaborator OTHER

  • Insel Gruppe AG, University Hospital Bern

    lead OTHER

Principal Investigators

  • Paul Krack, Prof. · Insel Gruppe AG, University Hospital Bern

Study Design

Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-01-03
Primary Completion
2026-12-31
Completion
2026-12-31

Countries

  • Czechia
  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05765110 on ClinicalTrials.gov