MedTrace Logo

Screening for Lung Cancer in Subjects With Family History of Lung Cancer

NCT05762731 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1520

Last updated 2023-03-10

No results posted yet for this study

Summary

Lung cancer can be detected via screening of high-risk individuals, i.e current or ex-heavy smokers, with low-dose computer tomography (LDCT) of thorax. The National Lung Screening Trial in US and the NELSON trial in Europe demonstrated reduction in lung cancer mortality with LDCT screening for lung cancer. In Hong Kong, however, there is a prominence of female never-smokers with lung cancer. There is no identifiable risk factors for non-smokers with lung cancer except family history of lung cancer. The hypothesis is that lung cancer screening for subjects with family history of lung cancer, can detect early lung cancer.

Conditions

Interventions

DIAGNOSTIC_TEST

Low dose CT thorax

A multi-detector row CT scanner with minimum section collimation of ≤1 mm and minimum number of data acquisition channels ≥ 16will be employed.

DIAGNOSTIC_TEST

Low dose CT thorax

Control subjects will also proceed to CT thorax, and outcome measures be compared to subjects

Sponsors & Collaborators

  • The Queen Elizabeth Hospital

    collaborator OTHER

  • Kwong Wah Hospital

    collaborator OTHER

  • Hong Kong Sanatorium & Hospital

    collaborator INDUSTRY

  • The University of Hong Kong

    lead OTHER

Eligibility

Min Age
50 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-02-01
Primary Completion
2024-12-31
Completion
2025-12-31

Countries

  • Hong Kong

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05762731 on ClinicalTrials.gov