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Alterations of Gut Microbiome, Function, and Its Intervention After Defunctioning Ileostomy

NCT05759741 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2023-03-14

No results posted yet for this study

Summary

This study focused on the alterations of gut microbiome and function during defunctioning ileostomy, and observed the effects of probiotic intervention on intestinal microbiome and function. The investigators looked forward to find the specific intestinal maladjusted flora from this work, which could provide a new scheme for the subsequent treatment of the damaged intestinal function and the reduction of the incidence of postoperative complication.

Conditions

  • Ileostomy - Stoma
  • Rectal Cancer
  • Microbial Disease
  • Intestinal Functional Disorder

Interventions

DRUG

MIYAIRI 588

4 tablets of MIYAIRI 588 were inserted into the distal ileostomy once a week for 6 months

Sponsors & Collaborators

  • Huashan Hospital

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-17
Primary Completion
2024-07-17
Completion
2024-07-17

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05759741 on ClinicalTrials.gov