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Effect of MgSO4 Pretreatment on Muscle Relaxation

NCT05757999 · Status: RECRUITING · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2024-07-01

No results posted yet for this study

Summary

In this study, the effect of magnesium sulphate on the onset and duration of intense and moderate cis-atracurium induced neuromuscular blocking and on the period of no response to nerve stimulation will be evaluated in patients who will recieve magnesium sulphate (intervention group) and patients who will not recieve magnesium sulphate (comparator group).

Conditions

  • Muscle Relaxation

Interventions

DRUG

Magnesium Sulphate

A magnesium sulphate infusion (60 mg kg-1, total volume 100 ml, infusion rate 10 ml min-1) will be administered to patients 10 min. before induction of anesthesia.

DRUG

Saline

The patients will be pretreated with an intravenous 0.9% saline infusion (total volume 100 ml, infusion rate 10 ml min-1) 10 min before induction of anesthesia.

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Hala Abdel-Ghaffar, MD · Professor of anesthesia and intensive care, faculty of medicine, Assiut university, Assiut, Egypt.

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-07-23
Primary Completion
2025-04-30
Completion
2025-05-31

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05757999 on ClinicalTrials.gov