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Discovering Cancer Risks From Environmental Contaminants and Maternal/Child Health

NCT05746169 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 1576

Last updated 2025-12-30

No results posted yet for this study

Summary

The DREAM Cohort is a longitudinal observational study developed to enhance our understanding of how multiple exposures to environmental chemicals and pollutants across a diverse population of pregnant women and their offspring are linked to cancer risks. Because pregnancy induces multiple maternal hormonal and physiological changes that can increase cancer susceptibility to environmental chemical exposures, this study will focus on pregnancy as a period of particular vulnerability to toxic agents.

Conditions

Interventions

OTHER

Health Questionnaires

A questionnaire with content developed and tested in the investigator's previous reproductive and cancer epidemiology studies as part of the NIH Environmental Influences on Child Health Outcomes (ECHO) consortium will be used to collect information on primary established and hypothesized risk factors for cancer and additional covariates.

OTHER

Specimen sample collection

Collection of blood, urine, nails, hair, and saliva samples will be obtained during the participant encounters.

Sponsors & Collaborators

Principal Investigators

  • Peggy Reynolds, PhD · University of California, San Francisco

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-09-01
Primary Completion
2025-07-21
Completion
2025-07-21

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05746169 on ClinicalTrials.gov